Select the favourable conditions required for the formation of oxyhaemoglobin at the alveoli.

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Question

Select the favourable conditions required for the formation of oxyhaemoglobin at the alveoli.

Accepted Answer

Correct Answer: B — High pO₂, low pCO₂, less H⁺, lower temperatureStep-by-step Solution:The formation of oxyhaemoglobin (HbO₂) is favoured by conditions prevailing in the pulmonary alveoli:High pO₂ (104 mm Hg): Drives oxygen to bind haemoglobin (rightward shift on O₂-Hb dissociation curve is not favoured here; high pO₂ ensures saturation).Low pCO₂: Reduces carbamino compound formation and favours O₂ binding (Haldane effect).Less H⁺ (higher pH/alkaline): Higher pH (less acidic) increases haemoglobin's affinity for O₂ (Bohr effect: low H⁺ shifts curve left, favouring association).Lower temperature: Lower temperature increases haemoglobin's affinity for O₂ (shifts O₂-Hb dissociation curve to the left).Opposite conditions (high pCO₂, high H⁺, high temperature, low pO₂) prevail at respiring tissues, favouring O₂ dissociation (release of O₂ from HbO₂).Key Concept: Bohr effect: increased CO₂, decreased pH (more H⁺), and increased temperature decrease haemoglobin's affinity for O₂, facilitating O₂ unloading at tissues. Reverse conditions at alveoli favour O₂ loading.

Select the favourable conditions required for the formation of oxyhaemoglobin at the alveoli.

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Select the favourable conditions required for the formation of oxyhaemoglobin at the alveoli.

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