The cofactor of the enzyme carboxypeptidase is:
(1) Zinc
(2) Niacin
(3) Flavin
(4) Haem

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Question

The cofactor of the enzyme carboxypeptidase is:
(1) Zinc
(2) Niacin
(3) Flavin
(4) Haem

Accepted Answer

Correct Answer: A — ZincStep-by-step Solution:Carboxypeptidase is a proteolytic enzyme that hydrolyzes the peptide bond at the C-terminal end of proteins. It is a metalloprotease that requires a metal ion as a cofactor. The specific cofactor for carboxypeptidase A and B is zinc (Zn²⁺). Zinc is bound to the active site and participates in the catalytic mechanism. Niacin (vitamin B3) is a precursor of NAD and NADP. Flavin (vitamin B2) is a cofactor for flavoproteins. Haem is a cofactor for cytochromes and hemoglobin. Therefore, the correct answer is Zinc.Key Concepts: Enzyme cofactors: metal ions (zinc, magnesium, etc.) and organic coenzymes. Metalloproteases, role of zinc in catalysis.

The cofactor of the enzyme carboxypeptidase is: (1) Zinc (2) Niacin (3) Flavin (4) Haem

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The cofactor of the enzyme carboxypeptidase is: (1) Zinc (2) Niacin (3) Flavin (4) Haem

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